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Norethisterone enanthate is a long-acting parenteral progestogen, orally active, and functions as a click chemistry reagent. It contains an alkyne group that can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing azide groups. This compound is intended for research use only.
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Bazedoxifene acetate is an oral, nonsteroidal selective estrogen receptor modulator (SERM) that acts as an inhibitor of IL-6/GP130 protein-protein interactions. It is used in research for osteoporosis and pancreatic cancer.
Small molecular GP130 inhibitor
Inhibits STAT3 phosphorylation induced by IL-6 and IL-11
Induces apoptosis in human pancreatic cancer cells
Inhibits STAT3 nuclear translocation induced by IL-6
Blocks cell migration in pancreatic cancer cells by inhibiting GP130
Inhibits Capan-1 tumor growth in mouse models
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Deoxycorticosterone acetate (56-47-3) is a small-molecule agonist targeting mineralocorticoid receptors (MR) It is designed to activate MR thereby regulating renal sodium reabsorption and potassium excretion Deoxycorticosterone acetate exerts its biological activity primarily through interaction with cytoplasmic mineralocorticoid receptors leading to nuclear translocation and modulation of electrolyte balance Typical IC50 values associated with its mineralocorticoid receptor binding affinity have been reported in the nanomolar range Based on these pharmacological properties Deoxycorticosterone acetate holds research potential in studies of electrolyte balance adrenal insufficiency modeling and the pathophysiology of hypertension as well as models investigating mineralocorticoid receptor-dependent signaling and renal or cardiovascular physiology
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Bazedoxifene (acetate)-D is the D-crystal form compound of Bazedoxifene acetate, an orally active, nonsteroidal selective estrogen receptor modulator (SERM) with IC50s of 23 nM for ERα and 99 nM for ERβ.
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C20 Ceramide is a naturally occurring 20:0 ceramide abundant in the brain. It is provided as a characterized, high-purity research reagent suitable for biochemical and cell biology studies involving sphingolipid metabolism.
Natural 20:0 ceramide abundant in the brain.
High purity (99.11%).
Molecular formula C38H75NO3; molecular weight 594.01.
Available in small milligram quantities (for example, 5 mg).
For research use only; not for clinical or human use.
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Also available in 2 mg 5 mg 10 mg 50 mg 100 mg and bulk. Please contact Fisher for quotes. Glatiramer acetate (GA) is a synthetic amino acid copolymer that is approved for treatment of relapsing remitting multiple sclerosis (RRMS) and clinically isolated syndrome (CIS). purity: 98%
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